Thyroid Cancer Brain Metastases and Thyroglobulin
نویسندگان
چکیده
منابع مشابه
Serum thyroglobulin and thyroid cancer.
Thyroglobulin is a large glycosylated protein (MW 660000 daltons) which is synthesised and secreted by the thyroid cell into the follicular lumen. In the thyroglobulin molecule the iodotyrosines undergo oxidative coupling to form the iodothyronines thyroxine (T4) and triiodothyronine (T3). Production of thyroid hormones results from micropinocytosis of iodinated thyroglobulin from the colloid i...
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A 45-year-old woman presented with a headache and visual complaints. Brain MRI revealed a large mass in the right occipital cortex. The tumor was surgically removed and pathological examination showed papillary carcinoma originating from thyroid gland. She had a history of thyroid surgery 27 years ago indicating papillary thyroid cancer with central neck lymph node involvement followed by no ad...
متن کاملThyroglobulin Measurement for Detecting Lymph Node Metastases in Thyroid Cancer Patients
Differentiated thyroid cancer (DTC), which includes papillary and follicular cancer, is responsible for 90% of all thyroid cancers (Sherma, 2003; Maseeh et al., 2013). According to the American Thyroid Association guidelines, the initial treatment for DTC consists of total or near-total thyroidectomy and cervical lymph node (LN) dissection with or without radioiodine (RAI) ablation (Cooper et a...
متن کاملImportance of measurement of thyroglobulin and anti-thyroglobulin antibodies in differentiated thyroid cancer.
Differentiated thyroid cancers include papillary and follicular carcinomas, both originating from follicular epithelium. Treatment of choice is usually total or near total thyroidectomy, followed by ablative radioiodine 131I treatment, and by the long-term administration of thyroid hormone. Despite its excellent prognosis, recurrent disease does occur in approximately 20-40% of patients. Guidel...
متن کاملLymph node metastases in papillary thyroid cancer detected by quantitative real-time polymerase chain reaction for thyroglobulin and cytokeratine-19.
Papillary thyroid cancer (PTC) metastases in the lymph nodes (LNs) were detected by real-time polymerase chain reaction (PCR) for TG and cytokeratin 19 (CK19), and the obtained results were compared with histopathology. 107 LNs from 34 PTC patients were divided into four blocks by a special cutting device - 2 for histopathology, while the other 2 were tested by quantitative real-time PCR. Metas...
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ژورنال
عنوان ژورنال: Journal of Endocrinology and Metabolism
سال: 2016
ISSN: 1923-2861,1923-287X
DOI: 10.14740/jem351w